Since 1989, the Treatment Research Program (TRP) has been committed to advancing the understanding and treatment of schizophrenia. Our mission is to improve the lives of individuals living with schizophrenia by conducting innovative research, including clinical trials of new medications and strategies that support recovery.

​

Challenges in Schizophrenia Treatment

While significant progress has been made in understanding schizophrenia over the past decade, the development of new treatments has lagged. Translating research breakthroughs into effective medications has proven difficult, and many patients still face barriers to achieving optimal outcomes due to the lack of personalized treatment approaches.

Current treatments often do not account for the complex and diverse nature of schizophrenia. Most therapies are developed based on broad diagnostic criteria, which doesn't reflect the individual differences in how the condition manifests. This one-size-fits-all approach leaves many patients without the tailored care they need.

​

The Need for Personalized Care

Schizophrenia affects people in different ways, and so do its treatments. As a result, successful treatment can be a struggle. At the TRP, we are driven by a commitment to personalized medicine—developing treatments that address the unique needs of each patient, rather than relying on generalized approaches.

 

Key Components of the Treatment Research Program

A cornerstone of the TRP is the partnership established between the Maryland Psychiatric Research Center and Spring Grove Hospital Center. This partnership unites leading clinical and research professionals, fostering collaboration to deliver cutting-edge, innovative care.

Additionally, the TRP operates a Brief Stay Unit (BSU)—a 3-bed, research-focused short-stay facility dedicated to early-phase clinical studies and challenge studies. The unit is fully equipped with emergency care resources and staffed by trained research professionals, ensuring the highest standards of safety and care.

The TRP also offers specialized consultation and referral services, including national initiatives like the clozapine program, which aims to overcome treatment barriers. Through partnerships with community health centers, clinics, and private practices, we extend research opportunities to as many individuals with schizophrenia as possible, even those living in the community.

 

Referral Process and Participation Opportunities

The TRP is actively enrolling new participants for a variety of research studies, including behavioral studies, medication trials, and more. We welcome individuals with and without a history of mental illness to participate. Our studies offer an opportunity to contribute to the advancement of schizophrenia research while receiving cutting-edge care.